Summary: Immune checkpoint blockade has become an effective approach to reverse the immune tolerance of tumor cells.Indoleamine 2,3-dioxygenase 1 (IDO1) is frequently upregulated in many MICELLAR WATER types of cancers and contributes to the establishment of an immunosuppressive cancer microenvironment, which has been thought to be a potential targ

A new methodology for the synthesis of wide-angle scanning seat tube spacer arrays is proposed.It is based on the formulation of the array design problem as a multi-objective one where, for each scan angle, both the radiated power density in the scan direction and the total reflected power are accounted for.A set of numerical Gastrointestinal Healt

Results of the fluid-structure co-simulations that were carried out as part of the FleksProp project are presented.The FleksProp project aims to establish better design procedures that take into account the hydroelastic behavior of marine propellers and thrusters.Part of the project is devoted to establishing good validation cases for fluid-structu

In the field of biomechanics, numerical procedures can be used to understand complex phenomena that cannot be analyzed with experimental setups.The use Diabetes Monitoring - Glucose Meter Test Strips of experimental data from human cadavers can present ethical issues that can be avoided by utilizing biofidelic models.Biofidelic models have been sho

We study a two-component dark matter model consisting of a Dirac fermion and a complex scalar charged under new U(1) gauge group in the hidden sector.The dark fermion seat tube spacer plays the dominant component of dark matter which explains the measured DM relic density of the Universe.It has no direct coupling to ordinary standard model particle